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. 2019 Oct 11;47(5):1415–1427. doi: 10.1042/BST20190254

Table 2. Comparison of apparent activation constants (Kact) for four PKA isoforms obtained by in vitro biochemical kinase assay.

Kact [µM]
PKA-Iα PKA-Iβ PKA-IIα PKA-IIβ
cAMP 0.085 0.038 0.080 0.19
007 14 18 >70 50
S-220 0.29 0.29 0.27 0.21
S-223 >1000 >1000 >25 >1000