. 2019 Sep 9;110(11):3584–3594. doi: 10.1111/cas.14180

Table 3.

IC₅₀ values for SHR‐A1403 and SHR152852 against the proliferation of parental and resistant HCC827 cells

Cell line	IC₅₀ (mean ± SD)^a
Cell line	SHR‐A1403 (ng/mL)	SHR152852 (nmol/L)
HCC827	918.9 ± 9.6	1.6 ± 0.1
HA1	11.8 ± 2.9 (77.9)^a	4.9 ± 0.7 (3.1)^b
HA2	>30 000.0	3.3 ± 1.2 (2.1)^b
HG1	26.6 ± 2.5 (34.5)^a	4.0 ± 2.1 (2.5)^b
HG2	17.8 ± 1.6 (51.6)^a	5.3 ± 0.8 (3.3)^b
HG3	99.4 ± 16.8 (9.2)^a	8.5 ± 3.2 (5.3)^b
HG4	130.8 ± 5.3 (7.0)^a	10.7 ± 0.0 (6.7)^b

IC₅₀ were determined using sulforhodamine B assays by treating cells with different concentrations of drugs for 72 h. Data are presented as means ± SD of three independent experiments.

Sensitivity ratio = IC₅₀ (HCC827)/IC₅₀ (resistant cells).

Resistance ratio = IC₅₀ (resistant cells)/IC₅₀ (HCC827).