Fig. 2.

Regulation of DREB1 gene(s) by various signaling pathways under abiotic/biotic stress. ICE1 positively regulates expression of DREB1/CBF, HOS1 negatively regulates expression of CBF2 and CBF3 genes by interfering with the functioning of ICE1 protein, MYB15 negatively regulates expression of DREB1/CBF, ICE1 negatively regulates expression of MYB15 and positively regulates expression of DREB1/CBF, DREB1C negatively regulates the expression of DREB1A and DREB1B genes, DEAR1 lead to suppression of DREB1/CBF expression under low-temperature stress and mediates the cross-talk between biotic and abiotic stress response pathways and confers resistance to pathogens in plants. HOS: high expression of somatically responsive; ICE1: inducer of CBF expression 1 protein; EAR: ethylene response factor-associated amphiphilic repression