Table 4.
Published studies | ORR | Median PFS | Median OS |
---|---|---|---|
Pagano et al. [14] | 55% (median DOR = 16.4 months) | – | 12.6 months (range, 0.5–75.8), with a survival at 5 years was 9.3% |
Musto et al. [15] | 60.8% (post 4 cycles) | 52.1% (15 months) | 65.2% (15 months) |
Musto et al. [16] | 92% | 8 months | 12 months |
D Arena et al. [17] | 79% | – | 55% (2 years) |
Colovic et al. [18] | 7/30 patients achieved remission | – | 4.5 months |
García-Sanz et al. [19] | 37% (ORR = 29% + PR = 8%) | – | 8 months |
Mahindra et al. [20] | |||
Autologous SCT | 76% (at transplant) | 34% at 3 years | 64% at 3 years |
Allogeneic SCT | 64% (at transplant) | 20% at 3 years | 39% at 3 years |
Drake et al. [21] Autologous SCT |
41.2% (at day 100 post SCT) |
– | 25.7 (19.5–31.9 months) |
Pagano et al. [14] SCT |
– |
HR for relapse 0.13, (95% CI 0.04–0.41) |
38.1 months (range 4.8–75.8 months) |
Our study Median follow up-22 months |
70% (post induction chemotherapy) |
11 months (95% C.I. 6.3–15.6) |
21 months (95% C.I. 1–49.8) |