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. 2019 Nov 1;9:15853. doi: 10.1038/s41598-019-52388-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Merged expression matrix analysis shows distinct transcriptional patterns in blood and spleen over the course of acute P. chabaudi infection. (a) Principal component analysis of gene expression values from blood (yellow) and spleen (blue). (b) Gene expression signatures between the two tissues (B = blood, S = spleen) in the time-series composed of the top 10 significant differentially expressed genes (power > 0.7; −1.5 < logFC > 1.5) from the merged expression matrix. Colour scale represents expression value Z scores.