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. 2019 Nov 1;9:15821. doi: 10.1038/s41598-019-51994-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Maximum level of transient suppression seen on the mainland following an island release of 100 homozygous drive individuals in the no invasion threshold scenario (s = 0.8 and h = 0.3) across combinations of different migration rates and initial frequencies of resistant alleles on the mainland. Different levels of suppression are denoted by different colors (see color key on figure). Low initial resistance frequencies depict pessimistic scenarios (mainland is almost entirely susceptible to the drive), while high initial resistance frequencies approach the private allele scenario discussed in the text. The white region of the figure denotes initial levels of resistance that exceed the threshold level above which drive cannot invade the mainland.