Table 3.
List of top 10 enriched GOs for the overlapping genes set from the CO genes ().
| Term ID | Term name | p-value | Intersection |
|---|---|---|---|
| KEGG:05150 | Staphylococcus aureus infection | 3.63·10−6 | HLA-DQB1, HLA-DRB1, HLA-DQA1, CFD, HLA-DRB5 |
| REAC:202430 | Translocation of ZAP-70 to Immunological synapse | 5.28·10−6 | HLA-DQB1, HLA-DRB1, HLA-DQA1, HLA-DRB5 |
| REAC:202427 | Phosphorylation of CD3 and TCR zeta chains | 1.03·10−5 | HLA-DQB1, HLA-DRB1, HLA-DQA1, HLA-DRB5 |
| REAC:389948 | PD-1 signaling | 1.26·10−5 | HLA-DQB1, HLA-DRB1, HLA-DQA1, HLA-DRB5 |
| GO:0042613 | MHC class II protein complex | 1.43·10−5 | HLA-DQB1, HLA-DRB1, HLA-DQA1, HLA-DRB5 |
| KEGG:05310 | Asthma | 1.77·10−5 | HLA-DQB1, HLA-DRB1, HLA-DQA1, HLA-DRB5 |
| KEGG:05330 | Allograft rejection | 4.48·10−5 | HLA-DQB1, HLA-DRB1, HLA-DQA1, HLA-DRB5 |
| KEGG:05332 | Graft-versus-host disease | 5.63·10−5 | HLA-DQB1, HLA-DRB1, HLA-DQA1, HLA-DRB5 |
| REAC:202433 | Generation of second messenger molecules | 6.11·10−5 | HLA-DQB1, HLA-DRB1, HLA-DQA1, HLA-DRB5 |
| GO:0042611 | MHC protein complex | 8.27·10−5 | HLA-DQB1, HLA-DRB1, HLA-DQA1, HLA-DRB5 |