Fig. 2.

The swst mutant mice have altered activity levels. (A) Homozygous mutant mice (s/s, n = 71) exhibited decreased total activity (wheel revolutions per day) as compared to heterozygous (s/+, n = 102) and WT littermates (+/+, n = 49). (B) This decrease in total activity in s/s mice was reflected in their reduced overall average activity per minute, although s/s mice had increased activity during the light phase (C). (D) The average number of activity bouts per day was increased in s/s mice, while bout length (E) and average activity per bout (F) were decreased. There were no differences between s/+ and +/+ littermates for any measure. *P < 0.01; **P < 0.0001.