Table 1.

The Most Important Effects Of Oleuropein

Property	Observed Effects	References
Antioxidant	Inhibits of oxidation of low-density lipoproteins (LDL)	54,55
	Scavenges nitric oxide; increase inducible nitric oxide synthase expression	56
	Induction of the inducible nitric oxide synthase in macrophages	57
	Increases the ability of LDL to resist oxidation; reduces the plasma levels of total, free, and esterified cholesterol	58
	Antioxidant effects in leukocytes	59
	Lower lipid peroxidation	57
Anti-inflamatory	Inhibitis lipoxygenase activity and the production of leukotriene B4	59
Anti-atherogenic	Reduces monocytoid cell adhesion to endothelium and reduces cell adhesion molecule-1 mRNA and protein	60
Anti-cancer	Inhibits growth cancer cells (LN-18, TF-1a, 786-O, T-47D, RPMI-7951, LoVo)	61
	Decreases breast cancer cell viability	62
	Reduces the viability of MCF-7 by inducing cell apoptosis	63
	Inhibits cell proliferation (MCF-7, T-24, BBCE)	64
Anti-microbial	Strong antimicrobial activity against gram-negative and gram-positive bacteria	65,66
	Antimicrobial activity against mycoplasma	67
	Able to inhibit the development of: Staphylococcus aureus, Salmonella enteritidis, Bacillus cereus, Klebsiella pneumoniae, Escherichia coli, Campylobacter jejuni, Helicobacter pylori	68–72
Antiviral	Antiviral against: herpes mononucleosis, hepatis virus, rotavirus, bovine rhinovirus, canine parvovirus, feline leukemia virus	73
	Antiviral against: respiratory syncytial virus and para-influenza type 3 virus	74