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Synthesis of 1-methyl-1H-pyrrolo[2,3-b]pyridine 26.
Reagents and conditions. a) NaH, MeI, THF, 0°C to rt ; b) HNO3, 0°C to rt ; c) 3,4-dimethoxyphenylboronic acid, Pd(PPh3)4, K2CO3, H2O, dioxane, 105°C ; d) H2, THF, rt ; e) nicotinoyl chloride, pyridine, THF, 1M NaOH, rt.
