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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Mol Cancer Ther. 2019 Aug 6;18(11):2124–2134. doi: 10.1158/1535-7163.MCT-19-0163

Figure 5. Neuregulin enhances colony formation in the presence of cetuximab, CDX-3379 addition reverses this autocrine pathway.

Figure 5.

Clonogenic survival of (A. and C.) FaDu-CR clone cell line and (B. and D.) CAL27 cells treated as described in Material and Methods. The results represent data from three independent experiments for each cell line. Data are represented as the mean ± standard error. An * indicates a significant difference vs CTX alone and an ** indicates a significant difference vs CTX + NRG (p ≤ 0.05).