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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Ann Allergy Asthma Immunol. 2019 Sep 9;123(5):503–506. doi: 10.1016/j.anai.2019.09.003

Figure 2. Suppression of mediator release from aspirin-activated eosinophils through EP2 receptor.

Figure 2

Figure 2

Eosinophils (n=7 subjects) were pre-incubated with PGE2 (10−6 and 10−7 M) or butaprost (10−6 and 10−7 M) for 30 min before activation with 10 mM LysASA for an additional 30 minutes. Supernatants were collected and CysLT (A) and LTB4 (B) levels quantified by EIA. Suppression is presented as percent of activity observed with LysASA stimulated cells. Data are presented as mean±SEM with *p<0.02 or **p<0.002 in comparison to unstimulated cells.