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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Ann Allergy Asthma Immunol. 2019 Sep 9;123(5):503–506. doi: 10.1016/j.anai.2019.09.003

Figure 3. Antagonism of eosinophil activation via EP receptors.

Figure 3

Figure 3

Eosinophils (n=3 subjects) were pre-incubated with an EP1 and EP3 antagonist (10−8 M) for 15 min followed by PGE2 (10−8 M) for 30 min before activation with 10 mM LysASA for an additional 30 minutes. Supernatants were collected and CysLT (A) and LTB4 (B) levels quantified by EIA. Suppression is presented as percent of activity observed with LysASA stimulated cells. Data are presented as mean±SEM with *p<0.05 in comparison to unstimulated cells.