Table 1.
Several micropeptides encoded by noncoding RNAs (ncRNAs) and their corresponding functions
| Peptide | Size (kDa) | Species | Function | Reference |
| MLN | ~5 | Mouse | Suppressing SERCA activity in skeletal muscle | Anderson et al., 2015 |
| SCL | ~3 | Drosophila | Suppressing SERCA activity in cardiac muscle | Magny et al., 2013 |
| DWORF | ~4 | Mouse | Enhancing SERCA activity in skeletal muscle | Nelson et al., 2016 |
| SPAR | ~10 | Mouse | Suppressing mTORC1 activation in skeletal muscle | Matsumoto et al., 2017 |
| Myomixer | ~9 | Mouse | Promoting myoblast fusion during muscle development | Bi et al., 2017 |
| HOXB-AS3 | ~6 | Human | Suppressing colon cancer growth | Huang et al., 2017 |
| STORM | ~6 | Human | Reducing the interaction of SRP19 and 7SL RNA | Min et al., 2017 |
| Circ-ZNF609 encoded | 30–40 | Mouse, human | Unknown | Legnini et al., 2017 |
| CircMbl3 encoded | 37.04 | Drosophila | Unknown | Pamudurti et al., 2017 |
MLN: myoregulin; SCL: sarcolamban; DWORF: dwarf open reading frame; SPAR: small regulatory polypeptide of amino acid response; HOXB-AS3: HOXB cluster antisense RNA 3; STORM: stress-and tumor necrosis factor-α (TNF-α)-activated open reading frame (ORF) micropeptide; SERCA: sarcoplasmic reticulum Ca2+-ATPase; mTORC1: mechanistic target of rapamycin complex 1; SRP19: signal recognition particle 19