Table 1.
Methods and Technical Parameters of Bioassays at KingMed Diagnostics Laboratory, Tianjin, China
| Biomarker | Method | Coefficient of Variation, % | Detection Limit | |
|---|---|---|---|---|
| Within-Assay | Between-Assay | |||
| HbA1C, % | High performance liquid chromatography | <1.16 | <1.27 | 3.85–17.80 |
| hsCRP, mg/L | Immunoturbidimetric assay | <2.94 | <2.09 | 0.10–140.00 |
| Total cholesterol, mmol/L | Oxidase method | <0.70 | <3.18 | 0.13–18.18 |
| HDL cholesterol, mmol/L | Direct method | <0.67 | <3.14 | 0.09–3.08 |
| LDL-cholesterol, mmol/L | Direct method | <1.38 | <2.90 | 0.22–14.14 |
| Triglycerides, mmol/L | Oxidase method | <0.41 | <3.64 | 0.12–9.78 |
| Glucose, mmol/L | Hexokinase | <0.40 | <2.50 | 0.13–39.58 |
| Uric acid, μmol/L | Uricase, catalase | <0.25 | <2.32 | 38.50–1044.00 |
| Cystatin C, mg/L | Immunoturbidimetric assay | <1.84 | <1.87 | 0.10–6.00 |
| Blood urea nitrogen, mmol/L | Enzymatic | <0.71 | <2.82 | 0.65–39.05 |
| Creatinine, μmol/L | Picric acid method | <1.87 | <4.34 | 22.85–2151.70 |
Abbreviations: HbA1C, glycated hemoglobin; hsCRP, high-sensitivity C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein.