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. 2019 Sep 5;188(11):2031–2039. doi: 10.1093/aje/kwz188

Table 3.

Posterior Median Hazard Ratios From Bayesian Sensitivity Analysis of the Association Between Body Composition and Head and Neck Cancer–Related Mortality, Carolina Head and Neck Cancer Epidemiology Study, North Carolina, 2002–2013

Variable Overall Mortality Head and Neck Cancer Mortality
Model 1a,b Model 2a,c Model 3a,d Model 1a,b Model 2a,c Model 3a,d
HRe 95% CrI HRe 95% CrI HRe 95% CrI HRe 95% CrI HRe 95% CrI HRe 95% CrI
FMI 1.04 1.00, 1.08 1.05 1.00, 1.10 1.04 1.00, 1.08 1.04 0.98, 1.10 1.05 0.98, 1.13 1.04 0.98, 1.10
LMI 0.90 0.85, 0.95 0.90 0.84, 0.95 0.89 0.84, 0.94 0.89 0.81, 0.98 0.89 0.81, 0.98 0.88 0.80, 0.98

Abbreviations: BMI, body mass index, CrI, credible interval; FMI, fat mass index; HR, hazard ratio; LMI, lean mass index.

a For each model, the logit of proportion of body fat was specified as a function of age, race, sex, and smoking status, which was then used to calculate the LMI (lean tissue (kg)/height (m)2) and FMI (adipose tissue (kg)/height (m)2).

b Priors for proportion of body fat model used parameters in Table 2.

c Priors for proportion of body fat model as in model 1 with mean for BMI coefficient multiplied by 0.90.

d Priors for proportion of body fat model as in model 1 with residual error multiplied by 1.10.

e Hazard ratios per unit increase, adjusted for age (continuous), sex, race, years smoked (0, 1–9, 10–19, 20–39, 40–49, ≥50), lifetime alcohol intake (nondrinkers and, in mL: ≤133,294, 133,295–747,550, ≥747,551), total intake of fruits (continuous), total intake of vegetables (continuous), number of comorbidities reported (cardiovascular disease, pulmonary disease, renal disease, diabetes, and other cancers), and stage (I/II vs. III/IV).