TABLE 4.
HRs (95% CIs)1 of coronary artery disease mortality according to quintiles of dietary pattern scores of participants in the Singapore Chinese Health Study (n = 58,065)
| Quintiles of score | ||||||
|---|---|---|---|---|---|---|
| 1 (low) | 2 | 3 | 4 | 5 (high) | P-trend | |
| Men, n | 7388 | 5040 | 4438 | 4168 | 4413 | |
| Cases/person-years | 492/129,374 | 365/88,290 | 290/78,644 | 286/74,668 | 290/79,367 | — |
| Median score | −1.58 | −0.64 | −0.07 | 0.54 | 1.57 | — |
| Age-adjusted HR | 1.00 | 0.99 (0.86, 1.13) | 0.85 (0.73, 0.98) | 0.84 (0.73, 0.97) | 0.83 (0.72, 0.96) | 0.002 |
| Lifestyle-adjusted HR2 | 1.00 | 1.01 (0.88, 1.16) | 0.88 (0.76, 1.02) | 0.93 (0.79, 1.08) | 0.96 (0.82, 1.11) | 0.331 |
| Multivariable-adjusted HR3 | 1.00 | 0.96 (0.83, 1.10) | 0.83 (0.71, 0.96) | 0.85 (0.73, 0.99) | 0.83 (0.71, 0.96) | 0.004 |
| Women, n | 4225 | 6573 | 7175 | 7445 | 7200 | |
| Cases/person-years | 204/79,687 | 309/125,221 | 265/138,018 | 287/143,965 | 228/139,867 | — |
| Median score | −1.32 | −0.60 | −0.05 | 0.53 | 1.54 | — |
| Age-adjusted HR | 1.00 | 0.95 (0.80, 1.14) | 0.75 (0.62, 0.90) | 0.81 (0.67, 0.96) | 0.73 (0.60, 0.88) | <0.001 |
| Lifestyle-adjusted HR | 1.00 | 0.97 (0.81, 1.16) | 0.79 (0.65, 0.95) | 0.89 (0.74, 1.07) | 0.85 (0.70, 1.03) | 0.063 |
| Multivariable-adjusted HR | 1.00 | 0.91 (0.76, 1.09) | 0.70 (0.58, 0.84) | 0.75 (0.63, 0.90) | 0.69 (0.56, 0.84) | <0.001 |
| Men and women combined4, n | 11,613 | 11,613 | 11,613 | 11,613 | 11,613 | |
| Cases/person-years | 696/209,061 | 674/213,511 | 555/216,662 | 573/218,633 | 518/219,234 | — |
| Median score | −1.46 | −0.62 | −0.06 | 0.54 | 1.55 | — |
| Age-adjusted HR | 1.00 | 0.97 (0.87, 1.08) | 0.80 (0.71, 0.89) | 0.82 (0.73, 0.92) | 0.77 (0.69, 0.87) | <0.001 |
| Lifestyle-adjusted HR | 1.00 | 0.99 (0.89, 1.11) | 0.84 (0.75, 0.94) | 0.91 (0.81, 1.02) | 0.90 (0.80, 1.02) | 0.037 |
| Multivariable-adjusted HR | 1.00 | 0.94 (0.84, 1.05) | 0.77 (0.69, 0.87) | 0.81 (0.72, 0.91) | 0.76 (0.68, 0.86) | <0.001 |
1
Estimates are HRs (95% CIs).
2
Lifestyle-adjusted model controlled for age, father's dialect, year of interview, cigarette smoking, education level, physical activity, BMI, and energy intake.
3
In addition to the covariables used in the lifestyle-adjusted model, adjusted for history of hypertension, and history of diabetes.
4
P-interaction for sex in the age-adjusted model, lifestyle-adjusted model, and multivariable-adjusted model, respectively, were 0.338, 0.395, and 0.230. All models were additionally adjusted for sex.