Table 1.
PD cases | Controls | |||||
---|---|---|---|---|---|---|
Malay | Chinese | Indian | Malay | Chinese | Indian | |
N551K (c.1653C>G), rs7308720 | ||||||
Wild type (C/C) | 155 | 239 | 72 | 113 | 214 | 81 |
Heterozygous mutant (C/G) | 13 | 38 | 4 | 18 | 54 | 8 |
Homozygous mutant (G/G) | – | 2 | – | 2 | 1 | – |
Allelic frequency (%) | ||||||
Wild type (C) | 96.1 | 92.5 | 97.4 | 91.7 | 89.6 | 95.5 |
Mutant (G) | 3.9 | 7.5 | 2.6 | 8.3 | 10.4 | 4.5 |
R1398H (c. 4193G>A), rs7133914 | ||||||
Wild type (G/G) | 155 | 233 | 71 | 115 | 215 | 80 |
Heterozygous mutant (G/A) | 13 | 45 | 5 | 16 | 53 | 8 |
Homozygous mutant (A/A) | – | 1 | – | 2 | 1 | 1 |
Allelic frequency (%) | ||||||
Wild type(G) | 95.6 | 91.5 | 96.7 | 92.5 | 89.8 | 93.6 |
Mutant (A) | 4.4 | 8.6 | 3.3 | 7.5 | 10.2 | 5.4 |