Table 3.
Genetic polymorphism frequency
| Variant | Classifications | Frequency |
|---|---|---|
| ABCB1 2677 G > T/A‡ | TT，TA and AA | 40 (32.8%) |
| GT and GA | 53 (43.4%) | |
| GG | 29 (23.8%) | |
| ABCB1 3435 C>T‡ | TT | 17 (13.9%) |
| TC | 54 (44.3%) | |
| CC | 51 (41.8%) | |
| ABCB1 2677 Allele§ | T/A | 133 (54.5%) |
| G | 111 (45.5%) | |
| ABCB1 3435 Allele§ | T | 88 (36.1%) |
| C | 156 (63.9%) | |
| Diplotype‡ | 2677G/3435C‐2677G/3435C | 37 (30.3%) |
| 2677T/A/3435T‐2677 T/A/3435T | 15 (12.3%) | |
| 2677†/3435†‐2677†/3435† | 70 (57.4%) |
†
Any combination of alleles that is not mutually exclusive with another diplotype consisting of the 2677 and 3435 SNPs.
‡
Number represents number of patients (percentage).
§
Number represents number of alleles (percentage).