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. 2019 Oct 30;6(6):ENEURO.0134-19.2019. doi: 10.1523/ENEURO.0134-19.2019

Table 2:

Chat-Mecp2-/y Mice have reduced survival but are not impaired on other behavioral phenotypes

Test Phenotype tested Phenotype present in Chat-Mecp2-/y mice ?
General health exam Weight NS from no transgene; Mecp2 flox
General health exam Stereotypies No
Elevated plus maze Anxiety-like behavior No
Light/dark box Anxiety-like behavior No
Open field arena Anxiety-like behavior No
Open field arena Hypo/hyperactivity No
Rotarod Motor learning NS from no transgene; Mecp2 flox
Rotarod Motor coordination NS from no transgene; Mecp2 flox
Grip strength meter Motor strength No
Prepulse inhibition Sensory gating No
Passive avoidance Contextual learning No
Aging of animal Reduced survival Yes