Table 1.
Association between race/ethnicity and early‐onset RCC (<50 years old) in National Cancer Database (n = 405 073)
| n | Age, mean (SD) | P | All subtypesa | ccRCC onlyb | |||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | ||||
| Racial/ethnic minority groups compared to NHWs | <.001 | <.001 | <.001 | ||||
| NHW | 302 230 | 63.2 (12.7) | Reference | Reference | |||
| AI/AN | 1811 | 58.5 (12.1) | 2.21 (1.88‐2.59) | 2.25 (1.89‐2.67) | |||
| NHB | 45 334 | 60.4 (12.4) | 1.52 (1.47‐1.59) | 1.31 (1.24‐1.39) | |||
| AA | 6390 | 61.4 (13.6) | 1.23 (1.12‐1.35) | 1.23 (1.11‐1.36) | |||
| HA | 49 308 | 60.4 (13.4) | 1.50 (1.44‐1.55) | 1.50 (1.44‐1.56) | |||
| HA groups compared to NHWs | <.001 | <.001 | <.001 | ||||
| NHW | Reference | Reference | |||||
| Mexican/Chicano | 3745 | 59.0 (13.2) | 1.73 (1.54‐1.94) | 1.73 (1.53‐1.96) | |||
| Puerto Rican | 866 | 60.0 (13.2) | 2.52 (2.01‐3.16) | 2.50 (1.91‐3.26) | |||
| Cuban | 798 | 63.6 (12.7) | 1.32 (1.02‐1.71) | 1.38 (1.01‐1.88) | |||
| South or Central American | 1464 | 58.3 (13.0) | 1.50 (1.26‐1.78) | 1.37 (1.12‐1.67) | |||
| Dominican | 269 | 60.4 (14.0) | 1.59 (1.01‐2.53) | 1.72 (0.93‐3.18) | |||
Abbreviations: AA, Asian American; AI/AN, American Indian and Alaska Native; ccRCC, clear cell renal cell carcinoma; HA, Hispanic American; NHB, Non‐Hispanic Black; NHW, Non‐Hispanic White; RCC, renal cell carcinoma.
a
Early‐onset (age < 50) compared to late‐onset (≥age 50) adjusting for gender, facility type, Charlson/Deyo Score, RCC histologic subtype, stage at diagnosis, and insurance type.
b
Early‐onset (age < 50) compared to late‐onset (≥age 50) adjusting for gender, facility type, Charlson/Deyo Score, stage at diagnosis, and insurance type.