FIGURE 1.
Nlrp3 deficiency increases lung innate cell recruitment during N. brasiliensis infection. WT and Nlrp3−/− mice were infected with N. brasiliensis (Nb) and day 2 postinfected lung alveolar (alv.) Mφ (CD11bloSiglec-F+CD11c+), neutrophil (CD11b+Siglec-F−Ly6G+), and eosinophil (CD11b+Siglec-F+) (A) frequencies of live cells and (B) absolute numbers were measured by flow cytometry. Data are representative (mean ± SEM) of four individual experiments with three to five mice per group (per experiment). **p < 0.01, ***p < 0.001, one-way ANOVA and Tukey–Kramer post hoc test).