Table 2.
Study | n | Country | Follow-up, months | Drop out, % | Age, mean ± s.d. | Male, % | Macroprolactinoma, % | Treatmenta | Overweight or obese at baseline, % | Baseline prolactin, mU/L mean ± s.d. | Baseline BMI, mean ± s.d. |
---|---|---|---|---|---|---|---|---|---|---|---|
Schwetz 2017 (25) | 53 | Austria | 9 | 0 | 39 ± 17 | 58 | 59 | CAB | – | 7607 ± 4414 | 27.9 ± 5.9 |
Iglesias 2016 (32) | 27 | Spain | 57 | 0 | 39 ± 13 | 100 | 74 | CAB | – | 43693 ± 27401 | 31.3 ± 5.1 |
Auriemma 2015 (26) | 32 | Italy | 24 | 0 | 42 ± 5 | 100 | 78 | CAB | 97 | 42996 ± 93443 | 31.7 ± 3.9 |
Auriemma 2014 (5) | 61 | Italy | 60 | 0 | 34 ± 10 | 21 | 33 | CAB | 64 | 16733 ± 5073 | 27.6 ± 5.3 |
Barbosa 2014 (33) | 21 | Brazil | 6 | 40 | – | – | 23 | CAB, BRC | 69 | 9080 ± 7034 | 29.3 ± 15.4 |
Ciresi 2013 (4) | 43 | Italy | 12 | 0 | 34 ± 11 | 19 | – | CAB | – | 3715 ± 5718 | 25.57 ± 5.18 |
Inancli 2013 (29) | 21 | Turkey | 6 | 0 | 30 ± 10 | 0 | 14 | CAB | 19b | 3201 ± 1230 | 27.1 ± 5.9 |
Berinder 2011 (6) | 14 | Sweden | 6 | 7 | 40 ± 14 | 43 | 43 | CAB, BRC | 21b | M:26809(2617–204,255) /F: 1511(1043–2787) | 25.8 ± 7.8 |
Silva 2011 (8) | 22 | Brazil | 6 | 37 | 42 ± 35 | 23 | 18 | CAB, BRC | 62 | 5720 ± 3621 | 29.2 ± 15.3 |
Serri 2006 (7) | 15 | Canada | 3 | – | 39 ± 13 | 47 | 13 | CAB | 47b | 20,160 ± 18,780 | 29 ± 6 |
Doknic 2002 (30) | 23 | Serbia | 6 | 0 | 37 ± 3 | 52 | 65 | BRC | 39c | 42,682 ± 37,429 | 27.5 ± 3.4 |
Medic 2015 (31) | 20 | Serbia | 4 | 0 | 30 ± 7 | 0 | 30 | CAB, BRC | – | 2919 ± 1102 | 24 ± 6.4 |
Pala 2015 (27) | 19 | India | 6 | 32 | 27 ± 6 | 5 | 21 | CAB | 37 | 2514 ± 2232 | 24.2 ± 4.0 |
Yavuz 2003 (28) | 16 | Turkey | 6 | 0 | 31 ± 10 | 0 | – | BRC | – | 3318 ± 1637 | 26.3 ± 5.3 |
aCabergoline (CAB); Bromocriptine (BRC)
bBMI > 30.
cBMI > 27.
F, female; M, male.