Table 3.

Scoring systems to predict IVIG resistance

	Egami36	Kobayashi37	Sano38
		Sodium ≤133 mmol/L (2 points)
	ALT >100 IU/L (1 point)	AST ≥100 IU/L (2 points)	AST ≥200 IU/L (1 points)
	Day of illness at initial treatment ≤4 (1 point)	Day of illness at initial treatment ≤4 (2 points)
		% neutrophils ≥80% (2 points)
	CRP ≥8 mg/dL (1 point)	CRP ≥10 mg/dL (1 point)	CRP ≥7 mg/dL (1 point)
	Age ≤6 months (2 points)	Age ≤12 months (1 point)
	Platelet count ≤30×104/mm3 (1 point)	Platelet count ≤30×104/mm3 (1 point)
			Total bilirubin ≥0.9 mg/dL (1 point)
High risk	≥3 points	≥5 points	≥2 points
Japanese populations:
Sensitivity (%)	78	86	77
Specificity (%)	76	68	86