| p97 (Rabbit polyclonal) | Homemade | Freire & Ramadan Labs |
| ATX3 (Mouse monoclonal; C‐1H9) | Merck Millipore | Cat# MAB5360; RRID:AB_2129339 |
| ATX3 (Rabbit ATX3 full‐length polyclonal) | Homemade | Freire & Ramadan Lab |
| RNF8 (Rabbit polyclonal) | Proteintech | Cat# 14112‐1‐AP* |
| RNF8 (Rabbit polyclonal) | Homemade | Ramadan Lab |
| Phospho‐γ‐H2AX (Ser139) (Rabbit polyclonal) | Novus Biologicals | Cat# NB100‐2280; RRID:AB_10000580 |
| Phospho‐ γ‐H2AX (Ser139) | GeneTex | Cat# GTX127342* |
| 53BP1 (Rabbit polyclonal) | Santa Cruz Biotechnology | Cat# sc‐22760; RRID:AB_2256326 |
| 53BP1 (Mouse monoclonal; C‐19) | BD Biosciences | Cat# 612523; RRID:AB_399824 |
| HA (Rabbit polyclonal) | Santa Cruz Biotechnology | Cat# sc‐805; RRID:AB_631618 |
| HA [clone 3F10] (Rat monoclonal) | Roche | Cat# 3F10; RRID:AB_2314622 |
| PCNA (Mouse monoclonal) | Abcam | Cat# ab29; RRID:AB_303394 |
| Vinculin (Mouse monoclonal; C‐VIN54) | Abcam | Cat# ab130007; RRID:AB_11156698 |
| Flag (Rabbit polyclonal) | Sigma‐Aldrich | Cat# F7425; RRID:AB_439687 |
| MDC1 (Mouse monoclonal; M2444) | Sigma‐Aldrich | Cat# M2444, RRID:AB_532268 |
| Ufd1(Rabbit polyclonal) | Homemade | Freire & Ramadan Labs |
| Npl4 (Rabbit polyclonal) | Homemade | Freire & Ramadan Labs |
| RNF168 (Rabbit polyclonal) | Homemade | Freire & Ramadan Labs |
| K48‐Ub (Rabbit monoclonal; C‐Apu2) | Merck Millipore | Cat# 05‐1307; RRID:AB_1587578 |
| K48‐Ub (human monoclonal) | Genentech | C‐Apu2.07 |
| K63‐Ub (Rabbit monoclonal; C‐Apu3) | Merck Millipore | Cat# 05‐1308; RRID:AB_1587580 |
| K63‐Ub (human monoclonal) | Genentech | C‐Apu3.A8 |
| FK2‐Ub (Mouse monoclonal; C‐FK2) | Enzo Life Sciences | Cat# BML‐PW8810; RRID:AB_10541840 |
| Proteasomal Subunit α6 | Enzo Life Sciences | Cat# BML‐PW8195, RRID:AB_10541045 |
| RAP80 (Rabbit polyclonal) | Bethyl | Cat# A300‐763A; RRID:AB_669796 |
| α‐Tubulin (Mouse monoclonal; DM1A) | Sigma‐Aldrich | Cat# T6199; RRID:AB_477583 |
| β‐Actin (Mouse monoclonal) | Abcam | Cat# ab6276; RRID:AB_2223210 |
| RAD51 (Rabbit polyclonal; H‐92) | Santa Cruz Biotechnology | Cat# sc‐8349; RRID:AB_2253533 |
| BRCA1 (Mouse monoclonal; C‐D‐9) | Santa Cruz Biotechnology | Cat# sc‐6954; RRID:AB_626761 |
| GFP (Goat polyclonal) | Santa Cruz Biotechnology | Cat# sc‐5385, RRID:AB_641121 |
| Cyclin E [clone HE12] (Mouse monoclonal) | Millipore | Cat# 05‐363; RRID:AB_2071085 |
| Cyclin A [clone H‐432] (Rabbit polyclonal) | Santa Cruz Biotechnology | Cat# sc‐751; RRID:AB_631329 |
| Lamin B1 (Rabbit polyclonal) | Thermo Fisher Scientific | Cat# PA5‐19468; RRID:AB_10985414 |
| Anti‐BRCA2 (Ab‐1) (Mouse monoclonal 2B) | Merck Millipore | Cat# OP95, RRID:AB_2067762 |
| Phospho‐RPA32 (S4/S8) (Rabbit polyclonal) | Bethyl | Cat# A300‐245A; RRID:AB_210547 |
| Rabbit IgG, HRP‐conjugated (goat polyclonal) | Sigma‐Aldrich | Cat# A9169; RRID:AB_258434 |
| Mouse IgG, HRP‐conjugated (rabbit polyclonal) | Sigma‐Aldrich | Cat# A9044; RRID:AB_258431 |
| Rat IgG, HRP‐conjugated (goat polyclonal) | Bio‐Rad | Cat# 5204‐2504; RRID:AB_619913 |
| Alexa Fluor 488, Goat Anti‐Mouse IgG (H+L) | Thermo Fisher Scientific | Cat# (A‐11001); RRID:AB_2534069 |
| Alexa Fluor 488, Goat Anti‐Rabbit IgG (H+L) | Thermo Fisher Scientific | Cat# A‐11034; RRID:AB_2576217 |
| Alexa Fluor 594, Goat Anti‐Mouse IgG (H+L) | Thermo Fisher Scientific | Cat# A‐11020; RRID:AB_141974 |
| Alexa Fluor 594, Goat Anti‐Rabbit IgG (H+L) | Thermo Fisher Scientific | Cat# A‐11012; RRID:AB_2534079 |
| Alexa Fluor 488, Goat Anti‐Human IgG (Fcγ fragment‐specific) | Jackson ImmunoResearch Laboratories | Cat# 109‐545‐008; RRID:AB_2337833 |
| DyLight 488 goat anti‐human | Thermo Fisher Scientific | Cat# SA5‐10102; RRID:AB_2556682 |
*
RRID for these antibodies could not be found.