Figure 4. cGAS accelerates γ‐irradiation‐induced depletion of bone marrow cells independently of STING.

• A–D
  Kinetics of in vivo depletion of indicated bone marrow cells in WT mice (n = 3) after γ‐irradiation (9 Gy).
• E–H
  Bone marrow cells in WT (n = 3) and cGAS^−/− (n = 3) mice 10 h post‐γ‐irradiation.
• I–L
  Bone marrow cells in Sting^−/− (n = 3) and cGAS^−/− Sting^−/− (n = 3) mice 10 h post‐γ‐irradiation.

Data information: Data in this figure are presented as mean ± SD. One‐way ANOVA followed by Sidak's post‐test. NS: P > 0.05, *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, and ****P ≤ 0.0001.