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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Protein J. 2019 Aug;38(4):389–408. doi: 10.1007/s10930-019-09862-3

Fig. 2. Schematics of Class I assembly pathways.

Fig. 2.

Type 5 secretion systems (autotransporters) rely on the GSP for delivery across the IM and then are recruited to the Bam complex for OM insertion and surface display. C-U (Chaperone - Usher) systems as exemplified by the Pap pilus assembly pathway. Pilin subunits bind a periplasmic chaperone, e.g., PapD, by donor-strand complementation (DSC) and are delivered to the OM usher for delivery across the OM and pilus assembly by donor-strand exchange (DSE). Type 8 secretion systems are responsible for assembly of curli amyloid fibers.