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. 2019 Sep 24;42(6):2255–2266. doi: 10.3892/or.2019.7332

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Copyright: © Dai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Kaplan-Meier plots showing the prognostic value of the identified disease-associated SNP pair and the corresponding gene pair. (A) Overall breast cancer survival for the SNP pair ANLN:rs12535394 and KDR:rs11133360. (B) Overall breast cancer survival for the SNP pair ANLN:rs10275489 and KDR:rs11941492. ‘SNPs=rare’ refers to rare homozygote, ‘SNPs=common’ represents either a common homozygote or heterozygote. (C) Overall breast cancer survival with concomitantly low expression of ANLN and KDR. ‘Genes=low’ refers to concomitant low expression of both genes, ‘Genes=not low’ includes cases where expression of at least one gene is not low. (D) Overall breast cancer survival with concomitantly high expression of ANLN and KDR. ‘Genes=high’ refers to concomitant high expression of both genes, ‘Genes=not high’ includes cases where expression of at least one gene is not high. SNP, single nucleotide polymorphism; ANLN, anillin actin-binding protein; KDR, kinase insert domain receptor.