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. 2019 Oct 10;42(6):2537–2549. doi: 10.3892/or.2019.7365

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Copyright: © Cai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — PC induces dysregulated metabolism in adipocytes. (A) Heatmap of RNA-sequencing expression of genes associated with lipid metabolism signature between adipocytes grown alone (A1-A3) and cocultured with Panc-1 (C1-C3). (B and C) Reverse transcription-quantitative PCR of lipid metabolism-associated genes in adipocytes grown alone, and cocultured in the presence of (B) Panc-1 or (C) Mia PaCa2. Data are presented as the mean ± standard deviation. *P<0.05; **P<0.01; ***P<0.001. PC, pancreatic cancer.