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. Author manuscript; available in PMC: 2019 Nov 4.
Published in final edited form as: ACS Comb Sci. 2018 Apr 3;20(5):277–281. doi: 10.1021/acscombsci.8b00001

Scheme 1.

Scheme 1.

Chemistry suitable for the construction of one bead one compound libraries by solid-phase synthesis. The red stars on the DNA indicate chemical modifications that would impede amplification of the encoding tag.