Table 2.

Multivariable analysis of clinical and biological features that correlate with OS, PFSPO, and OSPO.

Features	OS			PFSPO			OSPO
	HR	95% C.I.	P	HR	95% C.I.	P	HR	95% C.I.	P
Neutrophils/lymphocytes (N/L) ratio (<2 vs. >2)	7.15	1.40–36.61	0.018	3.10	1.09–8.81	0.034	3.93	0.95–16.21	0.058
Best response (complete response (CR) vs. others)	NI+	NI	NI	4.11	1.55–10.88	0.004	NI	NI	NI
ECOG PS (0 vs. others)	8.54	1.74–42.01	0.008	NI	NI	NI	7.31	1.76–30.35	0.006
Local approches (surgery vs. others)	0.28	0.11–0.67	0.004	NI	NI	NI	0.59	0.34–1.03	0.066
LDH < ULN	0.04	0.003–0.47	0.010	NI	NI	NI	NI	NI	NI
Progression-free survival (PFS) >11 months	0.003	<0.001–0.12	0.002	NI	NI	NI	NI	NI	NI

NI⁺: Not included.