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Effect of S4 on UVB-induced matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMP)-1 expression in human skin fibroblasts. The results were given as mean ± standard deviation (n = 3). Significant difference versus non-irradiation group: ###, p < 0.001. Significant difference versus non-treatment group: **, p < 0.01; **, p < 0.01; ***, p < 0.001.
