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. 2019 Oct 9;10(10):783. doi: 10.3390/genes10100783

Table 2.

The clinical characteristics in the cohort of COPD patients and the frequency of the comorbidities.

Characteristic COPD Patients
Smoking, pack-year, median (range) 40 (0.8–160)
GOLD classification
A 172 (26.1)
B 171 (25.9)
C 172 (26.1)
D 145 (21.9)
FEV1/FVC, %, mean (SD) 56.66 (21.6)
FEV1, %, mean (SD) 55.13 (22.0)
Cough 597/704 (84.8)
mMRC 1
0 59 (8.4)
1 168 (23.9)
2 238 (33.9)
3 166 (23.6)
4 72 (10.2)
Annual exacerbation rate
0 234 (33.2)
2 346 (49.1)
>2 124 (17.6)
Hospital admission 276 (39.2)
Number of comorbidities
0 117 (16.6)
1 203 (28.8)
2 201 (28.6)
≥3 183 (26)
Comorbidities
Pulmonary hypertension 49 (7%)
Arterial hypertension 353 (50.1%)
Lung cancer 72 (10.2%)
Cardiovascular diseases 196 (27.8%)
Diabetes mellitus 100 (14.2%)
Extrapulmonary neoplasms 63 (8.9%)
Chronic gastritis /GERD 71 (10.1%)
Chronic kidney disease 29 (4.1%)
Osteoporosis 35 (5%)
Psychiatric disorders 37 (5.3%)

Data are presented as number (%). 1 0, breathless with strenuous exercise; 1, shortness of breath when hurrying on the level or walking up a slight hill; 2, shortness of breath when walking its own pace on the level; 3, shortness of breath after walking about 100 m; 4, breathless when dressing. GOLD, Global Initiative for Chronic Obstructive Lung Disease; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; mMRC, modified Medical Research Council dyspnea; GERD, gastroesophageal reflux disease.