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. 2019 Sep 3;7(9):1189–1197. doi: 10.1177/2050640619873784

Table 3.

Association between median week 14 vedolizumab trough level (VTL) and clinical and endoscopic outcomes for all patients.a

Median W14 VTL, µg/ml IQR Median W14 VTL, µg/ml IQR p
W14 remitters 22.3 18.3–31.4 W14 non-remitters 15.6 9–20.9 0.0001
W14 remitters plus normal CRP 20.6 18.6–34.7 W14 non-remitters and/or without normal CRP 17.2 10.2–23.2 0.006
W22 remitters 22.4 18.6–32.2 W22 non-remitters 14.2 9–20.9 <0.0001
W22 remitters plus normal CRP 20.8 19–30.5 W22 non-remitters and/or without normal CRP 16.2 9.5–27.6 0.004
W54 remitters 20.9 16.9–31.4 W54 non-remitters 15.9 8.5–19.5 0.008
W54 remitters plus normal CRP 20 17.8–26.9 W54 non-remitters and/or without normal CRP 14.5 8–20.9 0.03
MH at W54 20.4 16.9–25.9 No MH at W54 11.9 7.3–17.4 0.0008

CRP: C-reactive protein; IQR: interquartile range; MH: mucosal healing.

a

MH data are referred to patients having both baseline and follow-up endoscopy.