Table 3.
Patient characteristics and telomere length changes.
| Patient Characteristic | Delta Telomere Length (>15% Baseline) | |||
|---|---|---|---|---|
| Shorter | Unchanged | Longer | p-Value | |
| Number of patients | 21 | 8 | 11 | |
| Age (years ± SD) | 45.38 *(±20.84) | 49.50 (±15.63) | 61.45 (±13.53) | 0.0712 |
| BMI (kg/m2 ± SD) | 29.04 (±7.98) | 28.35 (±8.12) | 25.74 (±2.98) | 0.4523 |
| Male/Female | 18/3 | 6/2 | 7/4 | 0.35813 |
| APACHE-II score (±SD) | 21 (±8) | 24 (±5) | 25 (±7) | 0.2562 |
| SOFA score | 9 (±3) | 10 (±3) | 11 (±4) | 0.3959 |
| WBC count (K/mcL ± SD) | 12.2 (±6.5) | 11.6 (±5) | 11.8 (±5.3) | 0.9557 |
| Platelet count (K/mcL ± SD) | 203 (±94) | 201 (±131) | 156 (±76) | 0.4128 |
| CRP | 16 (±13.3) | 15.5 (±12.4) | 11.6 (±13.1) | 0.7066 |
| Albumin | 3 (±0.9) | 2.8 (±0.9) | 3 (±0.6) | 0.8334 |
| pH | 7.3 (±0.11) | 7.25 (±0.12) | 7.31 (±0.11) | 0.4361 |
| Ventilated on admission | 21/21 | 7/8 | 9/11 | 0.14956 |
| Admission diagnosis | 0.48791 | |||
| trauma | 9 | 2 | 3 | |
| sepsis | 6 | 1 | 1 | |
| respiratory | 3 | 1 | 1 | |
| transplant | 1 | 1 | 1 | |
| other | 2 | 3 | 5 | |
| Medical/Surgical | 10/11 | 5/3 | 7/4 | 0.61399 |
*, p value <0.05.