Table 11.
Potential hotspots for rearrangement in the pig genome based on translocation frequency.
| Hotspot | Observed Breakpoints | Physical Cytogenetic Band Length (Mb) | Expected Breakpoints | X2 Value | Fold Change Between Observed and Expected | Translocation Frequency |
|---|---|---|---|---|---|---|
| 10q13 | 4 | 4.449 | 0.7 | 15.5571 | 5.7143 | 0.8991 |
| 11q11 | 3 | 3.413 | 0.54 | 11.2067 | 5.5556 | 0.879 |
| 12q15* | 5 | 5.798 | 0.91 | 18.3825 | 5.4945 | 0.8624 |
| 14q151 | 4 | 5.114 | 0.8 | 12.8 | 5 | 0.7822 |
| 9p24* | 7 | 9.302 | 1.46 | 21.0216 | 4.7945 | 0.7525 |
| 4q11 | 3 | 4.013 | 0.63 | 8.9157 | 4.7619 | 0.7476 |
| 6q11 | 3 | 4.078 | 0.64 | 8.7025 | 4.6875 | 0.7357 |
| 7q13* | 5 | 6.851 | 1.07 | 14.4345 | 4.6729 | 0.7298 |
| 15q26 | 4 | 5.628 | 0.88 | 11.0618 | 4.5455 | 0.7107 |
| 15q13* | 10 | 14.326 | 2.25 | 26.6944 | 4.4444 | 0.698 |
| 1q17*1 | 7 | 10.738 | 1.68 | 16.8467 | 4.1667 | 0.6519 |
| 2q13 | 3 | 4.73 | 0.74 | 6.9022 | 4.0541 | 0.6342 |
| 12p15 | 2 | 3.347 | 0.52 | 4.2123 | 3.8462 | 0.5976 |
| 14q11* | 6 | 10.177 | 1.6 | 12.1 | 3.75 | 0.5896 |
| 14q13 | 3 | 5.14 | 0.81 | 5.9211 | 3.7037 | 0.5837 |
| X2 = 194.759, d.f =14, p < 1 × 10−5, σest = 3.784, * = Band has both ≥5 breakpoints, and >0.58 translocation frequency, 1 = Band has a common fragile site | ||||||