Table 1.
TCGA Gene Expression Analysis.
| Gene | Poorly Differentiated LMS Subtype I: n = 22 |
Conventional LMS Subtype II: n = 32 |
Tests *, p-Value | |
|---|---|---|---|---|
| LMOD1 | 0.0002 ** | |||
| Median | 3.6 | 6.5 | ||
| Range | 8.3 | 10.4 | ||
| Mean | 3.3 | 5.9 | ||
| SD | 2.4 | 2.2 | ||
| ARL4C | 0.01 ** | |||
| Median | −0.003 | −0.7 | ||
| Range | 6.1 | 5.8 | ||
| Mean | 0.4 | −0.6 | ||
| SD | 1.6 | 1.3 | ||
| TUBB3 (β-3 Tubulin) | 0.0001 ** | |||
| Median | 1 | −0.6 | ||
| Range | 4.7 | 4.3 | ||
| Mean | 0.9 | −0.6 | ||
| SD | 1.4 | 1.2 | ||
| PTGER4 (EP4) | 0.14 | |||
| Median | 1.7 | 2.8 | ||
| Range | 5.6 | 6.6 | ||
| Mean | 1.5 | 2.2 | ||
| SD | 1.3 | 1.9 | ||
LMOD1, leiomodin-1; ARL4C, ADP ribosylation factor-like 4C; General Linear Model F1,52 = 16.67, p = 0.0002; * Comparison of distribution of biomarkers between Subtype I and Subtype II; ** p ≤ 0.01.