Table 1.
Characteristics of the study population.
| Group | Discovery Set | Validation Set | Participants of Screening Colonoscopy | ||||
|---|---|---|---|---|---|---|---|
| iDa (Clinical) CRC | ASTER (Mostly Screening) Controls | BLITZ Matched Set (Screening) | BLITZ (Screening) | ||||
| CRC | AA | Controls | AA | Controls | |||
| Total | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) |
| 96 | 94 | 56 | 101 | 102 | 623 | 4202 | |
| Age in years | |||||||
| 50–59 | 22 (23) | 25 (27) | 10 (18) | 22 (21) | 21 (21) | 237 (38) | 1916 (46) |
| 60–69 | 41 (43) | 44 (46) | 28 (50) | 49 (49) | 50 (49) | 247 (40) | 1614 (38) |
| 70–79 | 33 (34) | 25 (27) | 18 (32) | 30 (30) | 31 (30) | 139 (22) | 672 (16) |
| Mean | 64.8 | 64.1 | 66.0 | 65.5 | 65.4 | 63.3 | 61.9 |
| Median | 65.0 | 66.0 | 65.0 | 65.0 | 65.5 | 62.0 | 60.0 |
| SD | 7.0 | 7.4 | 5.8 | 6.6 | 6.9 | 5.9 | 6.5 |
| Gender distribution | |||||||
| Male | 59 (61) | 55 (59) | 36 (64) | 65 (64) | 66 (65) | 393 (63) | 1808 (43) |
| Female | 37 (39) | 39 (41) | 20 (36) | 36 (36) | 36 (35) | 230 (37) | 2394 (57) |
| Stage distribution | |||||||
| Stage I | 17 (18) | - | 17 (30) | - | - | - | - |
| Stage II | 31 (32) | - | 6 (11) | - | - | - | - |
| Stage III | 22 (23) | - | 26 (46) | - | - | - | - |
| Stage IV | 26 (27) | - | (13) | - | - | - | - |
| Early stage (I/II) | 48 (50) | - | 23 (41) | - | - | - | - |
| Late stage (III/IV) | 48 (50) | - | 33 (59) | - | - | - | - |
Abbreviations: AA—advanced adenoma; CRC—colorectal cancer; n—number; SD—standard deviation.