Table 4.
Functions of proteins from the identified five-marker signature.
| Biomarkers | Name | Uniprot ID | Molecular Function | Biological Process |
|---|---|---|---|---|
| AREG | amphiregulin | P15514 | cytokine, growth factor | Cell–cell signaling, cell proliferation |
| MASP1 | mannan-binding lectin serine protease 1 | P48740 | hydrolase, protease, serine protease | Complement activation lectin pathway, Immunity, Innate immunity |
| OPN/SPP1 | osteopontin | P10451 | cytokine | Biomineralization, Cell adhesion |
| PON3 | serum paraoxonase lactonase 3 | Q15166 | hydrolase | Calcium, Metal-binding |
| TR/TFRC | transferrin receptor protein 1 | P02786 | host cell receptor for virus entry, receptor | Endocytosis, Host–virus interaction |