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mRNA expression of TGF-β1, TGF-β RI and TGF-β RII investigated by qRT-PCR was significantly down-regulated (* p < 0.05; ** p < 0.01) in mice treated either orally with nanoparticle encapsulated Galunisertib (Ly os) or intravenously with the Galunisertib solution (Ly iv) as compared to controls (Vh).
