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. 2019 Oct 15;11(10):1567. doi: 10.3390/cancers11101567
ADP adenosine diphosphate
APC adenomatosis polyposis coli
APCs antigen-presenting cells
ATP adenosine triphosphate
CRC colorectal caner
ctDNA circulating tumor DNA
dMMR deficient mismatch repair
ICI immune checkpoint inhibitor
IHC immunohistochemistry
LS Lynch syndrome
mCRC metastatic colorectal cancer
MHC major histocompatibility complex
MMR mismatch repair
MSI microsatellite instability
MSS microsatellite stability
NGS next-generation sequencing
NCI national cancer institute
PCNA proliferating cell nuclear antigen
PCR polymerase chain reaction
PD-L1 programmed death ligand
pMMR proficient mismatch repair
TMB tumor mutational burden
LAG-3 lymphocyte activation gene 3
TIM-3 mucin domain-containing protein-3