Serotonin Receptor Subtypes and Their Potential Roles in the Development of Alcohol Abuse

Receptor Subtype	Potential Role in the Development of Alcohol Abuse
5-HT 1A	May control consummatory behavior, including alcohol consumption
5-HT 1B	May contribute to alcohol’s intoxicating effects May play a role in the development of tolerance to alcohol’s effects
5-HT2	May contribute to the development of alcohol withdrawal symptoms May play a role in alcohol’s rewarding effects
5-HT3	May regulate alcohol consumption May contribute to alcohol’s rewarding effects