Table 2.
Cat | Cmax (ng/mL) | Tmax (h) | T1/2 elim (h) | AUC 0-t (ng-h/mL) | MRT (h) |
---|---|---|---|---|---|
1 | 75 | 1 | 1.2 | 212 | 2.1 |
2 | 41 | 1 | 1.3 | 125 | 2.4 |
3 | 53 | 1 | 1.7 | 194 | 2.9 |
4 | 21 | 4 | 1.7 | 134 | 5.4 |
5 | 20 | 1 | 1.7 | 60 | 2.7 |
6 | 48 | 4 | 1.2 | 256 | 5.7 |
Mean + SE | 43 ± 9 | 2.0 ± 0.6 | 1.5 ± 0.1 | 164 ± 29 | 3.5 ± 1.4 |
Cmax = maximum concentration; Tmax = time of maximum concentration; T1/2 el = half-life of elimination; AUC 0-t = area under the curve (time 0 to 24 h); MRT = median residence time.