Table 6.

Cat (n = 8) mean and SEM of serum chemistry parameters immediately prior to (week 0), 4 weeks, 8 weeks and 12 weeks of an oral 2 mg/kg CBD dose twice daily using a CBD-rich hemp product.

Serum Chemistry (Ref. Range) **	Week 0	Week 4	Week 8	Week 12	p-Value
TP (5.2–8.8 g/dL)	7.2 ± 0.2	6.7 ± 0.2	7.1 ± 0.2	7.1 ± 0.2	0.94
Albumin (2.5–3.9 g/dL)	3.2 ± 0.1	3.2 ± 0.1	3.4 ± 0.1	3.2 ± 0.1	0.65
Globulin (2.3–5.3 g/dL)	4.0 ± 0.2	3.5 ± 0.2	3.8 ± 0.2	3.9 ± 0.2	0.72
AST (10–100 U/L)	21 ± 2	24 ± 4	24 ± 3	24 ± 3	0.17
ALT (10–100 U/L)	51 ± 5	90 ± 30	76 ± 17	75 ± 15	0.29
ALP (6–102 U/L)	30 ± 5	30 ± 6	29 ± 5	28 ± 6	0.53
GGT (1–10 U/L)	1 ± 0	1 ± 0	2 ± 0	1 ± 0	0.91
BUN (14–36 mg/dL)	23 ± 1	22 ± 1	20 ± 1 *	19 ± 1 *	<0.01
Creatinine (0.6–2.4 mg/dL)	1.3 ± 0.1	1.3 ± 0.0	1.3 ± 0.1	1.3 ± 0.1	0.84
Phosphorous (2.4–8.2 mg/dL)	4.5 ± 0.4	4.6 ± 0.4	4.3 ± 0.4	4.1 ± 0.2	0.06
Glucose (64–170 mg/dL)	90 ± 2	85 ± 2	88 ± 3	86 ± 3	0.25
Calcium (8.2–10.8 mg/dL)	9.6 ± 0.1	9.0 ± 0.1	9.5 ± 0.2	9.3 ± 0.1	0.72
Magnesium (1.5–2.5 mEq/L)	1.9 ± 0.1	1.8 ± 0.0	1.8 ± 0.0	1.8 ± 0.0	0.65
Sodium (145–158 mEq/L)	151 ± 1	153 ± 1	154 ± 1	151 ± 1	0.39
Potassium (3.4–5.6 mEq/L)	4.7 ± 0.2	4.7 ± 0.2	4.7 ± 0.3	4.5 ± 0.1	0.30
Chloride (104–128 mEq/L)	119 ± 1	121 ± 1	122 ± 1	119 ± 1	0.33
Cholesterol (75–220 mg/dL)	139 ± 9	123 ± 6	128 ± 6	123 ± 7	0.09
Triglycerides (25–160 mg/dL)	32 ± 1	28 ± 2	26 ± 2 *	25 ± 2 *	0.02
Creatine Kinase (59–529 U/L)	197 ± 31	113 ± 15 *	106 ± 12 *	126 ± 14 *	<0.01

* Represents a parameter that was significantly (p < 0.05) different from baseline. ** Klaassen, J.K. Reference values in veterinary medicine. Lab Med, 1999, 30, 194–197.