Table 1.
Clinical and demographic data.
Controls (n = 8) | AD patients (n = 8) | p value | |||
---|---|---|---|---|---|
Age | 63.0 (4.4) | 66.8 (5.9) | p = 0.17 | ||
Males/females (n) | 3/5 | 3/5 | NA | ||
MMSE | 29.8 (0.5) | 22.6 (3.3) | p < 0.001 | ||
Body weight (in kg) | 84.9 (14.6) | 84.6 (12.3) | p = 0.97 | ||
Body length (in cm) | 178.0 (12.9) | 178.4 (8.7) | p = 0.95 | ||
Test |
Retest |
Test |
Retest |
||
Injected dose (MBq) | 288 (42) | 283 (36) | 287 (39) | 316 (10) | pw = 0.24, pb = 0.17 |
Specific activity (µg/mL) | 3 (1) | 4 (1) | 3 (1) | 4 (1) | pw = 0.37, pb = 0.87 |
Note: Data are presented as mean (SD).
BPND: non-displaceable binding potential; pw: p value between test and retest measurements; pb: p value between AD and controls; SD: standard deviation; AD: Alzheimer’s disease; MMSE: Mini-Mental State Examination (range: 0–30); NA: not applicable.