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Serum MMP-2 (A) and MMP-9 (B) concentrations by treatment group (median, IQR and range) measured from samples at 14 days post-primary tumour excision (n = 12 animals per group). * indicates significant difference compared to group S (p < 0.05). • indicates outliers by Tukey’s method (>1.5 × IQR). Abbreviations: S, sevoflurane alone; S + L, sevoflurane and lidocaine; S + B, sevoflurane and bosutinib; S + B + L, sevoflurane, lidocaine and bosutinib.
