Table 1.

Homozygous and heterozygous private genetic variants in case 1 and case 2.

Filtering Step	Number of Variants
	Case 1	Case 2
homozygous variants in the whole-genome	2,791,220	2,384,739
homozygous protein-changing variants in the whole-genome	12,121	11,065
homozygous private protein-changing variants	4	9
homozygous private protein-changing variants in candidate genes	0	0
heterozygous variants in the whole-genome	3,080,790	4,346,318
heterozygous protein-changing variants in the whole-genome	10,310	13,789
heterozygous private protein-changing variants	31	276
heterozygous private protein-changing variants in candidate genes	1	1