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. 2019 Oct 2;11(10):1486. doi: 10.3390/cancers11101486

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Overexpression of migration and invasion enhancer 1 (MIEN1) attenuates cisplatin-induced cell apoptosis in PC-3 cells. (A) Cells (PC-DNA and PC-MIEN1) were treated with or without 80 μM cisplatin for 24 h. The fluorescence intensity for Annexin V-FITC in conjunction with PI staining was determined by flow cytometry (± standard error (SE), n = 4). (B) Data are presented as the percentage of apoptotic cells after cisplatin treatments. (C) Cell viability of PC-DNA and PC-MIEN1 cells after treatment with various dosages of cisplatin as indicated for 48 h (± SE, n = 8). ** p < 0.01.