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. 2019 Oct 22;9(10):288. doi: 10.3390/brainsci9100288

Table 1.

List of significant dysregulated miRNAs. For each miRNA, the log2FC, p-value, and the corresponding adjusted p-value from qPCR analysis have been detailed. The ROC section shows the results of AUC and associated p-value. The total number of miRNA targets (experimentally validated by reporter gene assays or computationally predicted by at least three algorithms) and the list of previously ADHD-associated target genes have been indicated.

miRNA Regulation qPCR ROC Target ADHD-Associated Target Genes
log2FC p-Value adj. p-Value AUC p-Value
miR-652-3p up 0.95594 2.84 × 10-3 1.83 × 10-2 0.733 2.33 × 10-2 89 B4GALT2, ANK3, SLC6A9
miR-148b-3p down −0.97755 2.85 × 10-3 1.83 × 10-2 0.878 5.46 × 10-6 8
miR-942-5p up 1.29942 4.22 × 10-3 1.83 × 10-2 0.811 1 × 10-4 2 TLE1
let-7b-5p up 1.49735 1.98 × 10-2 6.45 × 10-2 0.772 1.16 × 10-2 9
miR-181a-5p up 1.01275 2.82 × 10-2 7.33 × 10-2 0.75 1.82 × 10-2 75 TAF1, TRIO, SYNE1
miR-320a up 1.06673 4.02 × 10-2 8.72 × 10-2 0.778 1.16 × 10-2 8