Table 1.
Correlations between PATZ1 and the proneural and mesenchymal signature in pediatric glioblastoma (n = 34) 1.
| Proneural Signature | Mesenchymal Signature | ||||
|---|---|---|---|---|---|
| Gene | r 2 | p | Gene | r | p |
| PAFAH1B3 | 0.785 | 4.5 × 10−5 | ITGAM | −0.832 | 6.1 × 10−6 |
| LOC81691 | 0.745 | 1.4 × 10−4 | PLS3 | −0.817 | 1.3 × 10−5 |
| CHD7 | 0.713 | 3.7 × 10−4 | MAN1A1 | −0.780 | 5.5 × 10−5 |
| MAP2 | 0.673 | 1.0 × 10−3 | CASP4 | −0.776 | 5.9 × 10−5 |
| HDAC2 | 0.663 | 1.2 × 10−3 | S100A13 | −0.773 | 6.4 × 10−5 |
| MTSS1 | 0.639 | 2.2 × 10−3 | PTPRC | −0.768 | 7.7 × 10−5 |
| DLL3 | 0.633 | 2.5 × 10−3 | AMPD3 | −0.767 | 7.3 × 10−5 |
| SOX4 | 0.630 | 2.6 × 10−3 | ALOX5 | −0.755 | 1.0 × 10−4 |
| MARCKSL1 | 0.630 | 2.6 × 10−3 | VDR | −0.751 | 1.2 × 10−4 |
| HN1 | 0.624 | 3.0 × 10−3 | TNFRSF11A | −0.742 | 1.6 × 10−4 |
| PKMYT1 | 0.624 | 3.0 × 10−3 | CASP8 | −0.741 | 1.6 × 10−4 |
| PODXL2 | 0.620 | 3.2 × 10−3 | PLA2G5 | −0.741 | 1.6 × 10−4 |
| CASK | 0.614 | 3.6 × 10−3 | MFSD1 | −0.737 | 1.9 × 10−4 |
| DBN1 | 0.609 | 4.1 × 10−3 | RUNX2 | −0.732 | 2.1 × 10−4 |
| GNG4 | 0.609 | 4.1 × 10−3 | RAC2 | −0.726 | 2.7 × 10−4 |
| SEZ6L | 0.608 | 4.1 × 10−3 | CASP1 | −0.726 | 2.7 × 10−4 |
| SLCO5A1 | 0.605 | 4.4 × 10−3 | LY75 | −0.724 | 2.8 × 10−4 |
| MCM10 | 0.602 | 4.6 × 10−3 | CAST | −0.719 | 3.3 × 10−4 |
| CSNK1E | 0.598 | 5.0 × 10−3 | IL15 | −0.719 | 3.4 × 10−4 |
| RAB33A | 0.591 | 5.8 × 10−3 | LY96 | −0.717 | 3.4 × 10−4 |
| ASCL1 | 0.591 | 5.7 × 10−3 | TRIM38 | −0.709 | 4.2 × 10−4 |
| HMGB3 | 0.590 | 5.8 × 10−3 | ARSJ | −0.706 | 4.5 × 10−4 |
| SOX11 | 0.587 | 6.1 × 10−3 | SQRDL | −0.697 | 5.6 × 10−4 |
| AMOTL2 | 0.582 | 6.6 × 10−3 | TLR2 | −0.691 | 6.4 × 10−4 |
| OLIG2 | 0.576 | 7.3 × 10−3 | SYPL1 | −0.688 | 7.0 × 10−4 |
| DPF1 | 0.569 | 8.4 × 10−3 | PTRF | −0.684 | 7.8 × 10−4 |
| TOPBP1 | 0.567 | 8.6 × 10−3 | VAMP5 | −0.680 | 8.6 × 10−4 |
| CRMP1 | 0.566 | 8.8 × 10−3 | ITGB2 | −0.675 | 9.6 × 10−4 |
| SCPEP1 | −0.674 | 9.8 × 10−4 | |||
| PTGER4 | −0.672 | 1.0 × 10−3 | |||
| RAB27A | −0.667 | 1.2 × 10−3 | |||
| TNFRSF1A | −0.667 | 1.1 × 10−3 | |||
| CD14 | −0.667 | 1.2 × 10−3 | |||
| CHI3L1 | −0.666 | 1.2 × 10−3 | |||
| TRADD | −0.664 | 1.2 × 10−3 | |||
| IQGAP1 | −0.664 | 1.2 × 10−3 | |||
| LCP2 | −0.660 | 1.3 × 10−3 | |||
| MSR1 | −0.654 | 1.6 × 10−3 | |||
| ARPC1B | −0.653 | 1.6 × 10−3 | |||
| TGFBR2 | −0.649 | 1.8 × 10−3 | |||
| LAPTM5 | −0.647 | 1.8 × 10−3 | |||
| PHF11 | −0.646 | 1.9 × 10−3 | |||
| NPC2 | −0.643 | 2.0 × 10−3 | |||
| LAIR1 | −0.642 | 2.0 × 10−3 | |||
| CTSB | −0.641 | 2.1 × 10−3 | |||
| MAFB | −0.641 | 2.1 × 10−3 | |||
| NCF2 | −0.640 | 2.1 × 10−3 | |||
| ASL | −0.637 | 2.3 × 10−3 | |||
| ANXA1 | −0.637 | 2.3 × 10−3 | |||
| S100A11 | −0.629 | 2.6 × 10−3 | |||
| WWTR1 | −0.629 | 2.6 × 10−3 | |||
| COL8A2 | −0.626 | 2.9 × 10−3 | |||
| CSTA | −0.625 | 2.9 × 10−3 | |||
| IL4R | −0.619 | 3.3 × 10−3 | |||
| STAB1 | −0.617 | 3.4 × 10−3 | |||
| S100A4 | −0.613 | 3.7 × 10−3 | |||
| MGST2 | −0.609 | 4.1 × 10−3 | |||
| P4HA2 | −0.608 | 4.1 × 10−3 | |||
| MVP | −0.607 | 4.2 × 10−3 | |||
| MFSD1 | −0.601 | 4.7 × 10−3 | |||
| LCP1 | −0.599 | 5.0 × 10−3 | |||
| STAT6 | −0.593 | 5.5 × 10−3 | |||
| HFE | −0.592 | 5.7 × 10−3 | |||
| PLAUR | −0.592 | 5.7 × 10−3 | |||
| FCGR2B | −0.591 | 5.7 × 10−3 | |||
| ANXA4 | −0.589 | 5.9 × 10−3 | |||
| SP100 | −0.588 | 5.9 × 10−3 | |||
| COPZ2 | −0.584 | 6.4 × 10−3 | |||
| THBD | −0.584 | 6.4 × 10−3 | |||
| FCGR2A | −0.582 | 6.6 × 10−3 | |||
| CYBRD1 | −0.579 | 7.0 × 10−3 | |||
| LILRB3 | −0.579 | 7.0 × 10−3 | |||
| IL15RA | −0.576 | 7.4 × 10−3 | |||
| GNA15 | −0.574 | 7.6 × 10−3 | |||
| PTPN6 | −0.572 | 7.9 × 10−3 | |||
| SLC11A1 | −0.571 | 8.1 × 10−3 | |||
| CLCF1 | −0.570 | 8.2 × 10−3 | |||
| SYNGR2 | −0.566 | 8.9 × 10−3 | |||
| DSC2 | −0.560 | 9.9 × 10−3 | |||
1 GEO dataset GSE50161. 2 Correlations were analyzed by Pearson’s χ2 test through the R2 platform (http://r2.amc.nl).